Successful simple limbal epithelial transplantation (SLET) in lime injury-induced limbal stem cell deficiency with ocular surface granuloma

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Allo-limbal transplantation in patients with limbal stem cell deficiency.

AIM To report the outcome of a series of patients with stem cell deficiency who underwent allo-limbal transplantation and to describe a technique for this procedure. METHODS Six consecutive patients underwent allo-limbal stem cell transplantation. The primary diagnosis included alkali burn (n = 2), trachoma (n = 1), chronic rosacea blepharitis and kerato-conjunctivitis (n = 1), aniridia (n = ...

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Management of Unilateral Limbal Stem Cell Deficiency by Simple Limbal Epithelial Transplantation – Our Experience

Simple Limbal Epithelial Transplantation (SLET) has been proposed recently for care of total Limbal Stem Cell Deficiency (LSCD) secondary to alkali burn of cornea [1]. Reportedly it combines advantages of conjunctival limbal auto grafting [2] and cultivated limbal epithelial transplantation [3] by being a single-stage, affordable procedure utilizing minimal donor tissue. Besides, it is also rep...

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Ocular surface reconstruction in limbal stem cell deficiency

The purpose of our review was to familiarize the readers with the new concepts in ocular surface diseases and reconstruction. Limbal stem cell deficiency is characterized by the progressive invasion of conjunctival epithelial cells onto the cornea, superficial vascularisation, destruction of the corneal basement membrane, and chronic inflammatory cell infiltration. Depending on the severity of ...

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Cultivated limbal stem cell transplantation for ocular surface reconstruction

Severe damage to cell repair mechanisms of the limbal region can lead to many disorders such as vascularized conjunctivalization, keratinization, corneal scarring, and corneal opacification, collectively described as limbal stem cell deficiency (LSCD). Limbal stem cell deficiency may occur as a result of depletion of stem cells or destruction of their stromal niche. In such cases, apart from co...

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Cultivated limbal epithelial transplantation in children with ocular surface burns.

IMPORTANCE Although several reports are available on the use of conventional and cultured limbal epithelium using various substrates in the treatment of limbal stem cell deficiency (LSCD), the patient populations studied have been largely adults. Thus, to our knowledge, the outcomes of this procedure exclusively in a pediatric population have not been reported previously. OBJECTIVE To report ...

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ژورنال

عنوان ژورنال: Case Reports

سال: 2013

ISSN: 1757-790X

DOI: 10.1136/bcr-2013-009405